Article
[NO, a major regulator of metabolic and cardiovascular homeostasis].
Revue medicale de la Suisse romande - 1 Oct 2004
Thalmann Sébastien, Jayet Pierre-Yves, Duplain Hervé, Turini Pierre, Sartori Claudio, Vollenweider Peter, Scherrer Urs
Abstract excerpt
Obesity and insulin resistance are reaching epidemic proportions worldwide. Over the past decade, nitric oxide (NO) has emerged as a key player in the regulation of the metabolic and cardiovascular homeostasis. Here we will review recent data obtained in mice with disruption of the genes encoding for each of the three nitric oxide synthase isoforms. These data demonstrate that both defective and augmented NO...
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