Article

Hepatic ADMA–PRMT1 axis regulation is associated with NO-dependent endothelial dysfunction in MASH

2025-06-15

Abstract excerpt

Metabolic dysfunction-associated steatohepatitis (MASH) is a severe form of fatty liver disease and a recognized cardiovascular risk factor, yet the mechanisms linking hepatic pathology to vascular dysfunction remain poorly understood. We aimed to investigate whether MASH impairs endothelial function via nitric oxide (NO)-dependent mechanisms and to identify potential liver-derived mediators involved in this proce...

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Literature Corpus work: 82bf7511-ddc7-5615-9b90-5fa881613877
DOI: 10.1101/2025.06.10.658894

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