Article
DDAH gene and cardiovascular risk.
Vascular medicine (London, England) - 1 Jul 2005
Valkonen Veli-Pekka, Tuomainen Tomi-Pekka, Laaksonen Reijo
Abstract excerpt
The crucial role of nitric oxide (NO) for normal endothelial function is well known. In many conditions associated with increased risk of cardiovascular diseases such as hypercholesterolemia, hypertension, abdominal obesity, diabetes and smoking, NO biosynthesis is dysregulated, leading to endothelial dysfunction. The growing evidence from animal and human studies indicates that endogenous inhibitors of...
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