Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human Nitric Oxide Synthase-Its Functions, Polymorphisms, and Inhibitors in the Context of Inflammation, Diabetes and Cardiovascular Diseases.

International journal of molecular sciences - 23 Dec 2020

Król Magdalena, Kepinska Marta

Abstract excerpt

In various diseases, there is an increased production of the free radicals needed to carry out certain physiological processes but their excessive amounts can cause oxidative stress and cell damage. Enzymes play a major role in the transformations associated with free radicals. One of them is nitric oxide synthase (NOS), which catalyzes the formation of nitric oxide (NO). This enzyme exists in three forms (NOS1,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiovascular Diseases
Share to Diabetes Mellitus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Susceptibility

Share to Enzyme Inhibitors

Share to Insulin Resistance

Share to Molecular Targeted Therapy

Share to Nitric Oxide

Share to Nitric Oxide Synthase

Source

Open in PubMed Open full text

Identifiers

PMID: 33374571
DOI: 10.3390/ijms22010056
PMCID: PMC7793075

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human Nitric Oxide Synthase-Its Functions, Polymorphisms, and Inhibitors in the Context of Inflammation, Diabetes and Cardiovascular Diseases.PMID 33374571Read ↗

Endothelial nitric oxide synthase: From biochemistry and gene structure to clinical implications of NOS3 polymorphisms.Semantic proximity Read ↗

Genetic Factors of Nitric Oxide’s System in Psychoneurologic DisordersSemantic proximity Read ↗

Nitric oxide and the cardiovascular system: cell activation, vascular reactivity and genetic variant.Semantic proximity Read ↗

Nitric oxide in cellular adaptation and diseaseSemantic proximity Read ↗

Clinically relevant endothelial nitric oxide synthase polymorphisms and their impact on drug response.Semantic proximity Read ↗

Nitric oxide system and diabetic nephropathySemantic proximity Read ↗

Endothelial nitric oxide synthase gene: prospects for treatment of heart disease.Semantic proximity Read ↗

Nitric oxide synthases in the pathogenesis of cardiovascular diseaseSemantic proximity Read ↗

The Role of Inducible NOS2 Gene Polymorphism in the Development of Essential Arterial Hypertension.Semantic proximity Read ↗

Contribution of NOS3AS Variants to Susceptibility to Essential Hypertension: A Study in Kermanshah Province, Western Iran.Semantic proximity Read ↗

Nitric oxide synthase and its function in animal reproduction: an updateSemantic proximity Read ↗

[Molecular structure, regulatory mechanism and biological activity of endothelial nitric oxide synthase].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.