Article

Nitric oxide signaling in cardiac development, function and disease

2017-01-01

Abstract excerpt

A variety of roles have been attributed to Nitric Oxide (NO) in the cardiovascular system. During development, exposure of mouse embryonic stem cells to high levels of NO has been shown to promote cardiomyocyte differentiation through activation of transcription factors such as Nkx2.5. In adults, NO has been implicated in control of blood pressure and regulation of cardiac contractility. In disease, it is evident...

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Literature Corpus work: d0d8ca55-c3c5-5e4f-b608-ce08b3b1b6d4
DOI: 10.25560/68532

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