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The impact of methylarginine metabolism on disease progression in idiopathic pulmonary fibrosis

2018-01-01

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF) is a complex, progressive and irreversible lung disease of unknown aetiology with a median survival of only three years following diagnosis. Signatures of increased nitric oxide (NO) and its generating enzyme, inducible nitric oxide synthase (iNOS), are observed in experimental models of idiopathic pulmonary fibrosis (IPF). Asymmetric dimethylarginine (ADMA) competitively inhibi...

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Literature Corpus work
a3678e7e-d7f7-59fc-868e-f73ab92265a5
DOI
10.25560/80431
Open publication

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