Article

A shape-shifting nuclease unravels structured RNA

2021-11-30

Abstract excerpt

RNA turnover pathways ensure appropriate gene expression levels by eliminating unwanted transcripts that may otherwise interfere with cellular programs. The enzyme Dis3-like protein 2 (Dis3L2) is a 3’-5’ exoribonuclease that, through its RNA turnover activity, plays a critical role in human development 1 . Dis3L2 can independently degrade structured substrates and its targets include many coding and non-coding 3’...

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Literature Corpus work: 40fcde7b-54ce-5fc3-af69-183e706f20e6
DOI: 10.1101/2021.11.30.470623

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