Article

The RNA helicase DDX1 associates with the nuclear RNA exosome and modulates R-loops

2023-04-17

Abstract excerpt

The RNA exosome is a ribonuclease complex that mediates both RNA processing and degradation. This complex is evolutionarily conserved, ubiquitously expressed, and required for fundamental cellular functions, including rRNA processing. The RNA exosome plays roles in regulating gene expression and protecting the genome, including modulating the accumulation of RNA-DNA hybrids (R-loops). The function of the RNA exoso...

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Literature Corpus work: 2e04fb81-4cab-5dcf-80f7-db6a79f79e3f
DOI: 10.1101/2023.04.17.537228

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