Article
Repeated evolution of inactive pseudonucleases in a fungal branch of the Dis3/RNase II family of nucleases
2020-07-31
Abstract excerpt
The RNase II family of 3′-5′ exoribonucleases are present in all domains of life, and eukaryotic family members Dis3 and Dis3L2 play essential roles in RNA degradation. Ascomycete yeasts contain both Dis3 and inactive RNase II-like “pseudonucleases”. These function as RNA-binding proteins that affect cell growth, cytokinesis, and fungal pathogenicity. Here, we show how these pseudonuclease homologs, including Sac...
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Identifiers and source
- Literature Corpus work
- e43a4b2e-c656-58b2-a77f-44899f32afed
- DOI
- 10.1101/2020.07.30.229070