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Article

Spatial immune ecosystems govern therapeutic response in HER2-low breast cancer

2026-08-24

Abstract excerpt

HER2 low breast cancer represents a clinically important but biologically heterogeneous disease state, and the spatial immune programs underlying therapeutic response remain poorly understood. Here, we used single-cell spatial transcriptomics to characterize HER2 low and HER2 high breast tumors and define microenvironmental features associated with treatment sensitivity and resistance. We identified diverse malign...

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Literature Corpus work
40cc6891-d2a0-5741-9aa0-1dff3d7d8cba
DOI
10.64898/2026.08.19.745800
Open publication

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Spatial immune ecosystems govern therapeutic response in HER2-low breast cancerDOI 10.64898/2026.08.19.745800
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