Article
Breast cancer through the lens of whole transcriptome spatial imaging
2025-12-23
Abstract excerpt
Using the world’s first transcriptome-scale spatial imaging of a breast tumor, we assessed what could be learned about one patient’s disease. We cataloged heterogeneity across 3 morphological regions, 9 spatial domains, 37 cell types, and 1692 pathways. Then, employing a new algorithm for spatially stratified differential expression, we tested >2 million hypotheses about cell types’ behavior across space. We measu...
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Identifiers and source
- Literature Corpus work
- 8786e63e-da02-56f4-9147-da5017a81893
- DOI
- 10.64898/2025.12.19.695622