Article

Spatial organization of the tumor-immune microenvironment in ER-positive breast cancer: remodeling during treatment and associations with clinical response

2025-10-10

Abstract excerpt

<h4>Background</h4> The tumor microenvironment influences treatment response in ER-positive breast cancer, but what distinguishes responders from non-responders and how it changes during treatment is poorly understood. <h4>Methods</h4> ER-positive breast tumors treated with neoadjuvant chemotherapy with or without bevacizumab were profiled with bulk proteomics pre-(n = 95), on-(n = 84) and post-treatment (n = 10...

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Literature Corpus work: dcfc46c0-072f-54a3-b665-085b2e9bc0bd
DOI: 10.1101/2025.10.09.681336

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