Article

Midline Assembloids Reveal Regulators of Human Axon Guidance

2024-06-26

Abstract excerpt

Organizers are specialized cell populations that orchestrate cell patterning and axon guidance in the developing nervous system. Although non-human models have led to fundamental discoveries about the organization of the nervous system midline by the floor plate, an experimental model of human floor plate would enable broader insights into regulation of human neurodevelopment and midline connectivity. Here, we hav...

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Literature Corpus work: 40b23a57-8f70-5d04-b8d4-45c54bcf72ab
DOI: 10.1101/2024.06.26.600229

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