Article

Aberrant activation of wound healing programs within the metastatic niche facilitates lung colonization by osteosarcoma cells

2024-01-12

Abstract excerpt

<h4>Purpose: </h4> Lung metastasis is responsible for nearly all deaths caused by osteosarcoma, the most common pediatric bone tumor. How malignant bone cells coerce the lung microenvironment to support metastatic growth is unclear. The purpose of this study is to identify metastasis-specific therapeutic vulnerabilities by delineating the cellular and molecular mechanisms underlying osteosarcoma lung metastatic ni...

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Literature Corpus work: 40a94116-2098-5403-9fcb-e10d789f958d
DOI: 10.1101/2024.01.10.575008

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