Article

Temporal chromatin accessibility changes define transcriptional states essential for osteosarcoma metastasis

2022-11-16

Abstract excerpt

<title>Abstract</title> <p>The metastasis-invasion cascade describes the series of steps required for a cancer cell to successfully spread from its primary tumor and ultimately grow within a secondary organ. Despite metastasis being a dynamic, multistep process, most omics studies to date have focused on comparing primary tumors to the metastatic deposits that define end-stage disease. This static approach means...

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Literature Corpus work: 738e5bca-1d57-523b-8933-a8013056b519
DOI: 10.21203/rs.3.rs-2199384/v1

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