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A single-cell and spatially resolved atlas of human osteosarcomas

20 Aug 2024

Abstract excerpt

Osteosarcomas are intricate cellular ecosystems, where heterotypic interactions significantly influence disease progression and therapeutic outcomes. Despite their importance, a detailed understanding of their cellular composition and organizational structure remains elusive. In this study, we provide a comprehensive single-cell and spatially resolved transcriptomics analysis of human osteosarcomas. We construct...

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PMID: 39164791
DOI: 10.1186/s13045-024-01598-7

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