Article

Temporal chromatin accessibility changes define transcriptional states essential for osteosarcoma metastasis

2022-11-17

Abstract excerpt

The metastasis-invasion cascade describes the series of steps required for a cancer cell to successfully spread from its primary tumor and ultimately grow within a secondary organ. Despite metastasis being a dynamic, multistep process, most omics studies to date have focused on comparing primary tumors to the metastatic deposits that define end-stage disease. This static approach means we lack information about th...

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Literature Corpus work: 49b89aa1-5f96-5580-a6e1-e3000d636e84
DOI: 10.1101/2022.11.15.516627

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