Article

What We Know About Kininogen Structure – Importance for Function and Perspectives from Cryo-EM

2021-11-01

Abstract excerpt

Kininogens are multidomain glycoproteins found in the blood of most vertebrates. They are important in the blood coagulation cascade pathways - in intrinsic pathway activation leading to thrombin generation partially independently from tissue factor dependent extrinsic pathway, connecting blood coagulation with the kallikrein-kinin system. Nothing is known about the shape on atomic level therefore the endeavor to...

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Literature Corpus work: 409f33b2-30c5-5a24-afad-8bac3f818a0a
DOI: 10.20944/preprints202110.0342.v2

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