Article

Structure, dynamics and assembly of the ankyrin complex on human red blood cell membrane

2022-02-11

Abstract excerpt

<h4>Summary</h4> The cytoskeleton of red blood cell (RBC) is anchored to cell membrane by the ankyrin complex. This complex is assembled during RBC genesis and comprises primarily band 3, protein 4.2 and ankyrin, whose mutations contribute to numerous human inherited diseases. High-resolution structures of the ankyrin complex have been long sought-after to understand its assembly and disease-causing mutations. He...

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Literature Corpus work: cc944bde-546c-51c9-819c-6e4681d4c7e4
DOI: 10.1101/2022.02.10.480008

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