Back to search

Article

Bulk segregant analysis reveals environment × genotype interactions determining malaria parasite growth

2020-09-12

Abstract excerpt

What genes determine growth and nutrient utilization in asexual blood-stage malaria parasites? Competition experiments between a lab-adapted African parasite (NF54), and a recently isolated Asian parasite (NHP4026) reveal contrasting outcomes in different media: NF54 outcompetes NHP4026 in media containing human serum, while NHP4026 outcompetes NF54 in media containing AlbuMAX, a lipid-rich bovine serum formulatio...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
407aa34e-d5c4-5c8f-bce2-9d32d005eb4b
DOI
10.1101/2020.09.12.294736
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Bulk segregant analysis reveals environment × genotype interactions determining malaria parasite growthDOI 10.1101/2020.09.12.294736
A Malaria Parasite Cross Reveals Genetic Determinants of Plasmodium falciparum Growth in Different Culture MediaSemantic proximity
Bulk Segregant Approaches to Nutritional Genomics in Plasmodium falciparumSemantic proximity
Genetic mapping of fitness determinants across the malaria parasite <i>Plasmodium falciparum</i> life cycleSemantic proximity
Common host variation drives malaria parasite fitness in healthy human red cells.Semantic proximity
Common host variation drives malaria parasite fitness in healthy human red cellsSemantic proximity
Rapid identification of genes controlling virulence and immunity in malaria parasites.Semantic proximity
Genetic mapping of fitness determinants across the malaria parasite Plasmodium falciparum life cycleSemantic proximity
Quantitative Seq-LGS – Genome-Wide Identification of Genetic Drivers of Multiple Phenotypes in Malaria ParasitesSemantic proximity
Linkage maps from multiple genetic crosses and loci linked to growth-related virulent phenotype in Plasmodium yoelii.Semantic proximity
Nutrient limitation magnifies fitness costs of antimalarial drug resistance mutationsSemantic proximity
Optimizing bulk segregant analysis of drug resistance using Plasmodium falciparum genetic crosses conducted in humanized miceSemantic proximity
Genetically diverse Plasmodium falciparum infections, within-host competition and symptomatic malaria in humansSemantic proximity
Select a neighboring publication to make it the new centre.