Bulk Segregant Approaches to Nutritional Genomics in Plasmodium falciparum

Abstract excerpt

<title>Abstract</title> <p>Nutrient acquisition/metabolism pathways provide potent targets for drug design. We conducted crosses between African (NF54) and Asian (NHP4026) malaria parasites, and compared genome-wide allele frequency changes in independent progeny populations grown in human serum or AlbuMAX, a commercial bovine serum formulation. We <italic>detected </italic>three QTLs linked with differential gro...

Topics

Open a Topic to create a Post that cites this publication.

• Aquaculture disease management and microbiota
• Computational Drug Discovery Methods
• Evolution and Genetic Dynamics
• Invertebrate Immune Response Mechanisms
• Malaria Research and Control
• Mosquito-borne diseases and control
• Parasites and Host Interactions
• Trypanosoma species research and implications

Identifiers and source

Literature Corpus work

4031170a-4ebc-515f-a0d7-0f15079db452

DOI

10.21203/rs.3.rs-135739/v1