Article
Linkage maps from multiple genetic crosses and loci linked to growth-related virulent phenotype in Plasmodium yoelii.
Proceedings of the National Academy of Sciences of the United States of America - 2 Aug 2011
Li Jian, Pattaradilokrat Sittiporn, Zhu Feng, Jiang Hongying, Liu Shengfa, Hong Lingxian, Fu Yong, Koo Lily, Xu Wenyue, Pan Weiqing, Carlton Jane M, Kaneko Osamu, Carter Richard, Wootton John C, Su Xin-zhuan
Abstract excerpt
Plasmodium yoelii is an excellent model for studying malaria pathogenesis that is often intractable to investigate using human parasites; however, genetic studies of the parasite have been hindered by lack of genome-wide linkage resources. Here, we performed 14 genetic crosses between three pairs of P. yoelii clones/subspecies, isolated 75 independent recombinant progeny from the crosses, and constructed a...
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