Article

Nutrient limitation magnifies fitness costs of antimalarial drug resistance mutations

2021-08-02

Abstract excerpt

<h4>Summary</h4> Drug resistance mutations tend to disrupt key physiological processes, and therefore carry a fitness cost. The size of these fitness costs is a central determinant of the rate of spread of these mutations in natural populations so are important to quantify. Head-to-head competition assays provide a standard approach to measuring differential fitness, and have been used extensively for malaria par...

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Literature Corpus work: 6428e93c-3ef5-5bb4-b513-d53e52ad3e83
DOI: 10.1101/2021.08.02.454586

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