Article

Age-associated changes in knee osteoarthritis, pain-related behaviors, and dorsal root ganglia immunophenotyping of male and female mice

2022-07-08

Abstract excerpt

<h4>Objective</h4> Osteoarthritis (OA) is a leading cause of chronic pain, yet OA pain management remains poor. Age is the strongest predictor of OA development, and mechanisms driving OA pain are unclear. While injury-induced OA models are useful, only a subset of OA is linked to traumatic injury. Here, we aimed to characterize age-associated joint damage, mechanical sensitization, and dorsal root ganglia (DRG)...

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Literature Corpus work: 403fb4d5-bf37-581d-8da2-a5b0aeb77c7a
DOI: 10.1101/2022.07.07.499172

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