Article

Deep Proteome Profiling Reveals Signatures of Age and Sex Differences in Paw Skin and Sciatic Nerve of Naïve Mice

2022-07-04

Abstract excerpt

The age and sex of studied animals profoundly impact experimental outcomes in animal-based preclinical biomedical research. However, most preclinical studies in mice use a wide-spanning age range from 4 to 14 weeks and do not assess study parameters in male and female mice in parallel. This raises concerns regarding reproducibility and neglects potentially relevant age and sex differences. Furthermore, the molecul...

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Literature Corpus work: fab2279b-5d97-5a51-b35b-ca008d4661e9
DOI: 10.1101/2022.07.04.498721

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Deep Proteome Profiling Reveals Signatures of Age and Sex Differences in Paw Skin and Sciatic Nerve of Naïve MiceDOI 10.1101/2022.07.04.498721Read

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