Article

Development of primary osteoarthritis during aging in genetically diverse UM-HET3 mice

2023-12-17

Abstract excerpt

This study investigated the prevalence and progression of primary osteoarthritis (OA) in aged UM-HET3 mice. Using the Osteoarthritis Research Society International (OARSI) scoring system, we assessed articular cartilage (AC) integrity in 182 knee joints of 22-25 months old mice. Aged UM-HET3 mice showed a high prevalence of primary OA in both sexes. Significant positive correlations were found between cumulative A...

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Literature Corpus work: 69ac0be5-f75d-5993-876c-642f7f985242
DOI: 10.1101/2023.12.16.571693

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