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Meta-analysis and multi-omics to elucidate pathogenic mechanisms of age-related knee osteoarthritis

2021-05-07

Abstract excerpt

Increased mechanistic insight into the pathogenesis of knee osteoarthritis (KOA) is needed to develop efficacious disease-modifying treatments. Though age-related pathogenic mechanisms are most relevant to the great majority of KOA seen clinically, the bulk of our mechanistic understanding of KOA has been derived using surgically induced post-traumatic OA (PTOA) models. Here, we took an integrated approach of meta...

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Literature Corpus work
b74d40b5-7f1a-59a1-a3d2-6cdc04e2c1c7
DOI
10.1101/2021.05.06.442993
Open publication

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Meta-analysis and multi-omics to elucidate pathogenic mechanisms of age-related knee osteoarthritisDOI 10.1101/2021.05.06.442993
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