Article

Optimization of Multi-Ancestry Polygenic Risk Score Disease Prediction Models

2024-04-19

Abstract excerpt

<h4>Background</h4> Polygenic risk scores (PRS) have ushered in a new era in genetic epidemiology, offering insights into individual predispositions to a wide range of diseases. However, despite recent marked enhancements in their predictive power, there are still challenges that need to be overcome before PRS-based models can be broadly applied in the clinic, including sufficient accuracy, easy interpretability a...

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Literature Corpus work: b351685c-4bbf-5b77-90ce-2928ae6b71b9
DOI: 10.1101/2024.04.17.24305723

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