Article
The utility of obesity polygenic risk scores from research to clinical practice: A review.
Obesity reviews : an official journal of the International Association for the Study of Obesity - 1 Nov 2024
Jansen Philip R, Vos Niels, van Uhm Jorrit, Dekkers Ilona A, van der Meer Rieneke, Mannens Marcel M A M, van Haelst Mieke M
Abstract excerpt
Obesity represents a major public health emergency worldwide, and its etiology is shaped by a complex interplay of environmental and genetic factors. Over the last decade, polygenic risk scores (PRS) have emerged as a promising tool to quantify an individual's genetic risk of obesity. The field of PRS in obesity genetics is rapidly evolving, shedding new lights on obesity mechanisms and holding promise for...
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