Article

Recovery from transgenerational RNA silencing is driven by gene-specific homeostasis

2017-06-11

Abstract excerpt

Changes in gene expression that last for multiple generations without changes in gene sequence have been reported in many plants and animals 1–3 . Cases of such transgenerational epigenetic inheritance (TEI) could support the ancestral origins of some diseases and drive evolutionary novelty. Here, we report that stably expressed sequences in C. elegans have features that provide a barrier against TEI. By using d...

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Literature Corpus work: 3bd05022-8de8-5c6a-88a7-911d51186312
DOI: 10.1101/148700

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