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<i>Caenorhabditis elegans</i> heterochromatin factor SET-32 plays an essential role in transgenerational establishment of nuclear RNAi-mediated epigenetic silencing

2018-01-29

Abstract excerpt

Epigenetic inheritance contributes fundamentally to transgenerational physiology and fitness. Mechanistic understanding of RNA-mediated chromatin modification and transgenerational epigenetic inheritance, which in C. elegans can be triggered by exogenous double-stranded RNA (exo-dsRNA) or facilitated by endogenous small interfering RNAs (endo-siRNAs), has mainly been limited to the post-initiation phases of silen...

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Literature Corpus work
b0e30fdf-dda5-50be-a0ca-f0b7b40ee4f1
DOI
10.1101/255562
Open publication

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