Article

Gene silencing by double-stranded RNA from <i>C. elegans</i> neurons reveals functional mosaicism of RNA interference

2018-08-16

Abstract excerpt

<h4>ABSTRACT</h4> Delivery of double-stranded RNA (dsRNA) into animals can silence genes of matching sequence in diverse cell types through mechanisms that have been collectively called RNA interference. In the nematode C. elegans , dsRNA from multiple sources can trigger the amplification of silencing signals. Amplification occurs through the production of small RNAs by two RNA-dependent RNA polymerases (RdRPs)...

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Literature Corpus work: 466fa4cb-56e8-5d21-b1bc-c089ca21aafe
DOI: 10.1101/393074

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