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Article

Treg fitness as a biomarker for disease activity in Juvenile Idiopathic Arthritis

2024-04-28

Abstract excerpt

Juvenile Idiopathic Arthritis (JIA) is an autoimmune condition characterised by persistent flares of joint inflammation. However, no reliable biomarker exists to predict the erratic disease course. Normally, regulatory T cells (Tregs) maintain immune tolerance, with altered Tregs associated with autoimmunity. Treg signatures have shown promise in monitoring other autoimmune conditions, therefore a Treg gene and/or...

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Literature Corpus work
3fdce505-5ab4-5933-b479-b8bd60fef927
DOI
10.1101/2024.04.24.590917
Open publication

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Treg fitness as a biomarker for disease activity in Juvenile Idiopathic ArthritisDOI 10.1101/2024.04.24.590917
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