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Expression of CD49f defines subsets of human regulatory T cells with divergent transcriptional landscape and function that correlate with ulcerative colitis disease activity

2021-02-23

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Adoptive regulatory T cell (Treg) therapy is being trialled for treatment of different autoimmune disorders, including inflammatory bowel diseases (IBD). In-depth understanding of the biological variability of Treg in the human blood may be required to improve IBD immune monitoring and treatment strategies. <h4>Methods</h4> Through a combination of quantitative proteomic, mu...

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Literature Corpus work
87795d71-21b6-564a-9a24-4399382a6a13
DOI
10.1101/2021.02.22.432185
Open publication

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Expression of CD49f defines subsets of human regulatory T cells with divergent transcriptional landscape and function that correlate with ulcerative colitis disease activityDOI 10.1101/2021.02.22.432185
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