Article

The DCC receptor regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation

2020-08-03

Abstract excerpt

The forebrain hemispheres are predominantly separated during embryogenesis by the interhemispheric fissure (IHF). Radial astroglia remodel the IHF to form a continuous substrate between the hemispheres for midline crossing of the corpus callosum (CC) and hippocampal commissure (HC). DCC and NTN1 are molecules that have an evolutionarily conserved function in commissural axon guidance. The CC and HC are absent in...

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Literature Corpus work: 3fc918e3-3433-5059-81b9-9ed07efa74ea
DOI: 10.1101/2020.08.03.233593

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