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A novel role for the <i>CNTN6</i> locus in lumenization and radial glial cell fate determination during early human cortical development revealed in cerebral organoids

2025-10-10

Abstract excerpt

Neurodevelopmental disorders are a class of heterogeneous diseases with a significant genetic contribution, including pathologies resulting from copy number variations (CNVs). Recent advancements in genetic diagnostic technologies have led to the identification of new genes associated with neurodevelopmental disorders through CNVs. One such gene is CNTN6 , whose variants and CNVs are associated with intellectual...

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Literature Corpus work
5858011a-36be-5c21-9907-b8b118d36241
DOI
10.1101/2025.10.09.681391
Open publication

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A novel role for the <i>CNTN6</i> locus in lumenization and radial glial cell fate determination during early human cortical development revealed in cerebral organoidsDOI 10.1101/2025.10.09.681391
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