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Article

Gli3 controls corpus callosum formation by positioning midline guideposts during telencephalic patterning.

Cerebral cortex (New York, N.Y. : 1991) - 1 Jan 2014

Magnani Dario, Hasenpusch-Theil Kerstin, Benadiba Carine, Yu Tian, Basson M Albert, Price David J, Lebrand Cécile, Theil Thomas

Abstract excerpt

The corpus callosum (CC) represents the major forebrain commissure connecting the 2 cerebral hemispheres. Midline crossing of callosal axons is controlled by several glial and neuronal guideposts specifically located along the callosal path, but it remains unknown how these cells acquire their position. Here, we show that the Gli3 hypomorphic mouse mutant Polydactyly Nagoya (Pdn) displays agenesis of the CC and...

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Identifiers

PMID: 23042737
DOI: 10.1093/cercor/bhs303
PMCID: PMC3862269

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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