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Article

Neuronal basic helix-loop-helix proteins Neurod2/6 regulate cortical commissure formation before midline interactions.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 9 Jan 2013

Bormuth Ingo, Yan Kuo, Yonemasu Tomoko, Gummert Maike, Zhang Mingyue, Wichert Sven, Grishina Olga, Pieper Alexander, Zhang Weiqi, Goebbels Sandra, Tarabykin Victor, Nave Klaus-Armin, Schwab Markus H

Abstract excerpt

Establishment of long-range fiber tracts by neocortical projection neurons is fundamental for higher brain functions. The molecular control of axon tract formation, however, is still poorly understood. Here, we have identified basic helix-loop-helix (bHLH) transcription factors Neurod2 and Neurod6 as key regulators of fasciculation and targeted axogenesis in the mouse neocortex. In Neurod2/6 double-mutant mice,...

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Identifiers

PMID: 23303943
DOI: 10.1523/JNEUROSCI.0899-12.2013
PMCID: PMC6704922

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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