Article
Punctuated mutagenesis promotes multi-step evolutionary adaptation in human cancers
2025-07-04
Abstract excerpt
The rate of acquisition of genomic changes in cancer has been the topic of much discussion, with several recent investigations finding evidence of punctuated evolution instead of gradual accumulation of such changes. Despite forays into the description and quantification of these punctuated events, the effects of such changes on subsequent cancer evolution remain incompletely understood. Here we investigate how no...
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Identifiers and source
- Literature Corpus work
- 3fbf7c40-6a42-54ea-b1c4-b8cb2a301885
- DOI
- 10.1101/2025.06.30.662384