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Article

Evolutionary dynamics of tumor progression with random fitness values.

Theoretical population biology - 1 Aug 2010

Durrett Rick, Foo Jasmine, Leder Kevin, Mayberry John, Michor Franziska

Abstract excerpt

Most human tumors result from the accumulation of multiple genetic and epigenetic alterations in a single cell. Mutations that confer a fitness advantage to the cell are known as driver mutations and are causally related to tumorigenesis. Other mutations, however, do not change the phenotype of t...

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Identifiers

PMID: 20488197
DOI: 10.1016/j.tpb.2010.05.001
PMCID: PMC2929987

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20488197-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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