Article

The Genetic Architecture of Dietary Iron Overload and Associated Pathology in Mice

2023-06-07

Abstract excerpt

Tissue iron overload is a frequent pathologic finding in multiple disease states including non-alcoholic fatty liver disease (NAFLD), neurodegenerative disorders, cardiomyopathy, diabetes, and some forms of cancer. The role of iron, as a cause or consequence of disease progression and observed phenotypic manifestations, remains controversial. In addition, the impact of genetic variation on iron overload related ph...

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Literature Corpus work: 3f70b300-7122-5155-942e-1b6e13b9f149
DOI: 10.1101/2023.06.05.543764

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