Article

Investigating the genetic relationship between depression symptoms and Alzheimer’s Disease in clinically diagnosed and proxy cases

2023-06-06

Abstract excerpt

Depression is a risk factor for Alzheimer’s disease (AD), but evidence for their genetic relationship is mixed. Assessing depression symptom specific genetic associations may better clarify this relationship. Using data from the UK Biobank, the GLAD Study and PROTECT, we performed the largest genome-wide meta-analyses (GWAS) of the nine depression symptom items, plus their sum score, on the Patient Health Question...

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Literature Corpus work: 3f6546fc-8233-51b4-bc1c-e891d4588102
DOI: 10.1101/2023.06.05.23290588

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