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Article

The GWAS Risk Genes for Depression May Be Actively Involved in Alzheimer's Disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2018

Ni Hua, Xu Min, Zhan Gui-Lai, Fan Yu, Zhou Hejiang, Jiang Hong-Yan, Lu Wei-Hong, Tan Liwen, Zhang Deng-Feng, Yao Yong-Gang, Zhang Chen

Abstract excerpt

Depression is one of the most frequent psychiatric symptoms observed in people during the development of Alzheimer's disease (AD). We hypothesized that genetic factors conferring risk of depression might affect AD development. In this study, we screened 31 genes, which were located in 19 risk loci for major depressive disorder (MDD) identified by two recent large genome-wide association studies (GWAS), in AD...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 30010129
DOI: 10.3233/JAD-180276

Genes

NEGR1
OAT
SORCS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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