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TFU72 is a novel and potent DNA-PKcs inhibitor for enhancing homology-directed repair gene editing

2026-03-11

Abstract excerpt

Precise gene editing through homology directed repair (HDR) is one of the most versatile genome editing approaches with broad applications. Achieving high HDR gene editing efficiency is critical to realizing the full potential of this approach. Although many strategies have been explored to enhance HDR editing efficiency, inhibition of DNA-dependent protein kinase catalytic subunit (DNA-PKcs), a key component of t...

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Literature Corpus work
3eebe634-2089-5764-a502-82b0468acad0
DOI
10.64898/2026.03.10.710954
Open publication

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TFU72 is a novel and potent DNA-PKcs inhibitor for enhancing homology-directed repair gene editingDOI 10.64898/2026.03.10.710954
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