Article
Global computational alignment of tumor and cell line transcriptional profiles
2020-03-26
Abstract excerpt
Cell lines are key tools for preclinical cancer research, but it remains unclear how well they represent patient tumor samples. Identifying cell line models that best represent the features of particular tumor samples, as well as tumor types that lack in vitro model representation, remain important challenges. Gene expression has been shown to provide rich information that can be used to identify tumor subtypes,...
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Identifiers and source
- Literature Corpus work
- 3eb760d9-7ff9-5036-80a9-9a48cc386077
- DOI
- 10.1101/2020.03.25.008342