Article

Transcriptional fidelity enhances cancer cell line selection in pediatric cancers

2021-10-01

Abstract excerpt

Multi-omic technologies have allowed for comprehensive profiling of patient-derived tumor samples and the cell lines that are intended to model them. Yet, our understanding of how cancer cell lines reflect native pediatric cancers in the age of molecular subclassification remains unclear and represents a clinical unmet need. Here we use Treehouse public data to provide an RNA-seq driven analysis of 799 cancer cell...

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Literature Corpus work: cac7baa9-adbb-5c0f-84d2-f87cbd81b441
DOI: 10.1101/2021.10.01.462682

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