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Article

Comprehensive comparison of molecular portraits between cell lines and tumors in breast cancer

1 Aug 2016

Abstract excerpt

BACKGROUND: Proper cell models for breast cancer primary tumors have long been the focal point in the cancer's research. The genomic comparison between cell lines and tumors can investigate the similarity and dissimilarity and help to select right cell model to mimic tumor tissues to properly evaluate the drug reaction in vitro. In this paper, a comprehensive comparison in copy number variation (CNV), mutation,...

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PMID: 27556158
DOI: 10.1186/s12864-016-2911-z

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