Article

Comprehensive transcriptomic analysis of cell lines as models of primary tumor samples across 22 tumor types

2018-09-20

Abstract excerpt

Cancer cell lines are commonly used as models for cancer biology. While they are limited in their ability to capture complex interactions between tumors and their surrounding environment, they are a cornerstone of cancer research and many important findings have been discovered utilizing cell line models. Not all cell lines are appropriate models of primary tumors, however, which may contribute to the difficulty i...

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Literature Corpus work: 5f833581-51e1-5ff9-b940-eb710567b06e
DOI: 10.1101/422592

Open publication

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