Article

satuRn: Scalable analysis of differential transcript usage for bulk and single-cell RNA-sequencing applications

2022-08-08

Abstract excerpt

Alternative splicing produces multiple functional transcripts from a single gene. Dysregulation of splicing is known to be associated with disease and as a hallmark of cancer. Existing tools for differential transcript usage (DTU) analysis either lack in performance, cannot account for complex experimental designs or do not scale to massive single-cell transcriptome sequencing (scRNA-seq) datasets. We introduce s...

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Literature Corpus work: 3e74b17d-cc16-5ca3-ad61-8d997ab3f33b
DOI: 10.12688/f1000research.51749.2

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