Article

<i>satuRn:</i> Scalable Analysis of differential Transcript Usage for bulk and single-cell RNA-sequencing applications

2021-01-16

Abstract excerpt

Alternative splicing produces multiple functional transcripts from a single gene. Dysregulation of splicing is known to be associated with disease and as a hallmark of cancer. Existing tools for differential transcript usage (DTU) analysis either lack in performance, cannot account for complex experimental designs or do not scale to massive scRNA-seq data. We introduce satuRn, a fast and flexible quasi-binomial ge...

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Literature Corpus work: 0b6f593b-1c3a-59aa-8d37-6222d6645dec
DOI: 10.1101/2021.01.14.426636

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